By Greg Arnold, DC, CSCS, October 9, 2014, abstracted from “The effect of green tea on blood pressure and lipid profile: A systematic review and meta-analysis of randomized clinical trials” in the August 2014 issue of Nutrition, Metabolism & Cardiovascular Diseases

 

 

One in three US deaths results from cardiovascular disease (1). Major risk factors include high blood pressure and high cholesterol (“dyslipidemia”) (2). A new study (3) suggests green tea may help maintain normal blood pressure and appropriate blood lipid levels.

Researchers analyzed 20 trials involving 1536 participants and found “a significant reduction in systolic blood pressure, the upper reading measured during heart-muscle contraction, favouring green tea.” Specifically, intake up to 200 mg daily, described as five to six cups, significantly reduced systolic pressure by 1.94 mmHg. The best blood-pressure results appeared after at least 12 weeks of use.

Green tea intake up to 200 mg daily for at least 12 weeks also significantly reduced total cholesterol and
LDL
cholesterol. No effect was observed on
HDL.

Explaining blood-pressure effects, researchers cited laboratory work identifying green tea antioxidants acting similarly to antihypertensive medicines known as inhibitors of
ACE (Angiotensin Converting Enzyme inhibitor
) (4,5). For blood lipids, they cited animal studies in which green tea extracts inhibited intestinal fat absorption and increased the sensitivity of
LDL
receptors in the liver (
6,7).

Green tea significantly reduced systolic pressure, total cholesterol and
LDL
cholesterol, although the effect on systolic pressure was described as small and the effect on total and
LDL
cholesterol as modest.

Further independent long-term clinical trials to assess green tea’s effects are therefore warranted.

 

 

Reference:

1.     “Cardiovascular Disease at a Glance” posted on the CDC website

2.     “Risk Factors: Coronary Heart Disease” posted on the CDC website

3.     Onakpoya I.  The effect of green tea on blood pressure and lipid profile: A systematic review and meta-analysis of randomized clinical trials. Nutr Metab Cardiovasc Dis2014 Aug;24(8):823-36. doi: 10.1016/j.numecd.2014.01.016. Epub 2014 Jan 31

4.     Actis-Goretta L, Ottaviani JI, Fraga CG. Inhibition of angiotensin converting enzyme activity by flavanol-rich foods. J Agric Food Chem 2006 Jan 11;54(1):229e34

5.     Guerrero L,Castillo J,QuiñonesM,Garcia-Vallvé S,Arola L,PujadasG, et al. Inhibition of angiotensin-converting enzyme activity by flavonoids: structure-activity relationship studies. PLoS ONE 2012; 7(11):e49493

6.     Bursill CA, Abbey M, Roach PD. A green tea extract lowers plasma cholesterol by inhibiting cholesterol synthesis and upregulating the LDL receptor in the cholesterol-fed rabbit. Atherosclerosis 2007;193:86e93. of cholesterol in rats. Biochem Biophys Acta 1992;1127:141e6

7.     Bursill CA, Roach PD. A green tea catechin extract upregulates the hepatic low-density lipoprotein receptor in rats. Lipids 2007;42:621e7

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