{"id":16801,"date":"2024-06-23T11:15:48","date_gmt":"2024-06-23T08:15:48","guid":{"rendered":"https:\/\/marshal.co.il\/?p=16801"},"modified":"2026-10-29T00:57:05","modified_gmt":"2026-10-28T21:57:05","slug":"%d0%bf%d0%be%d0%bc%d0%be%d0%b3%d0%b0%d0%b5%d1%82-%d0%bb%d0%b8-%d1%8d%d0%ba%d1%81%d1%82%d1%80%d0%b0%d0%ba%d1%82-%d0%b7%d0%b5%d0%bb%d1%91%d0%bd%d0%be%d0%b3%d0%be-%d0%ba%d0%be%d1%84%d0%b5-%d1%81%d0%bd","status":"publish","type":"post","link":"https:\/\/marshal.co.il\/ru\/%d0%bf%d0%be%d0%bc%d0%be%d0%b3%d0%b0%d0%b5%d1%82-%d0%bb%d0%b8-%d1%8d%d0%ba%d1%81%d1%82%d1%80%d0%b0%d0%ba%d1%82-%d0%b7%d0%b5%d0%bb%d1%91%d0%bd%d0%be%d0%b3%d0%be-%d0%ba%d0%be%d1%84%d0%b5-%d1%81%d0%bd\/","title":{"rendered":"\u041f\u043e\u043c\u043e\u0433\u0430\u0435\u0442 \u043b\u0438 \u044d\u043a\u0441\u0442\u0440\u0430\u043a\u0442 \u0437\u0435\u043b\u0451\u043d\u043e\u0433\u043e \u043a\u043e\u0444\u0435 \u0441\u043d\u0438\u0437\u0438\u0442\u044c \u0432\u0435\u0441?"},"content":{"rendered":"
Abstracted by Tatjana Djakovic, MS, from “Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects in the January 18, 2012 issue of Diabetes Metabolic Syndrome and Obesity: Targets and Therapy<\/div>\n

\u041e\u0436\u0438\u0440\u0435\u043d\u0438\u0435 \u2014 \u0433\u043b\u043e\u0431\u0430\u043b\u044c\u043d\u0430\u044f \u044d\u043f\u0438\u0434\u0435\u043c\u0438\u044f, \u043c\u0430\u0441\u0448\u0442\u0430\u0431\u044b \u043a\u043e\u0442\u043e\u0440\u043e\u0439 \u0443\u0434\u0432\u043e\u0438\u043b\u0438\u0441\u044c \u0441 1980 \u0433\u043e\u0434\u0430. \u0412 2008 \u0433\u043e\u0434\u0443 \u0438\u0437\u0431\u044b\u0442\u043e\u0447\u043d\u044b\u0439 \u0432\u0435\u0441 \u0438\u043c\u0435\u043b\u0438 1.5 \u043c\u0438\u043b\u043b\u0438\u0430\u0440\u0434\u0430 \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0445 \u043e\u0442 20 \u043b\u0435\u0442, \u0447\u0442\u043e \u0441\u043e\u0437\u0434\u0430\u0432\u0430\u043b\u043e \u043e\u0433\u0440\u043e\u043c\u043d\u0443\u044e \u044d\u043a\u043e\u043d\u043e\u043c\u0438\u0447\u0435\u0441\u043a\u0443\u044e \u043d\u0430\u0433\u0440\u0443\u0437\u043a\u0443 (1). \u041e\u0436\u0438\u0440\u0435\u043d\u0438\u0435 \u2014 \u0432\u0430\u0436\u043d\u044b\u0439 \u0444\u0430\u043a\u0442\u043e\u0440 \u0440\u0438\u0441\u043a\u0430 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439, \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0430, \u0434\u0438\u0430\u0431\u0435\u0442\u0430 2 \u0442\u0438\u043f\u0430 \u0438 \u0440\u0430\u043a\u0430. \u041a\u043e\u0444\u0435 \u043f\u0440\u0438\u0432\u043b\u0451\u043a \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u0435\u0439 \u043a\u0430\u043a \u0441\u0442\u0438\u043c\u0443\u043b\u044f\u0442\u043e\u0440, \u0441\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0439 \u0432 \u0440\u044f\u0434\u0435 \u0440\u0430\u0431\u043e\u0442 \u0441\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u043c \u0432\u0435\u0441\u0430 \u0438 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u044c\u043d\u044b\u043c \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u0435\u043c \u0440\u0438\u0441\u043a\u0430 \u0442\u044f\u0436\u0451\u043b\u044b\u0445 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0431\u043e\u043b\u0435\u0437\u043d\u0435\u0439 (2).
\n\u041d\u0435\u0434\u0430\u0432\u043d\u0435\u0435 22-\u043d\u0435\u0434\u0435\u043b\u044c\u043d\u043e\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u0438\u0437\u0443\u0447\u0430\u043b\u043e, \u0441\u043d\u0438\u0436\u0430\u0435\u0442 \u043b\u0438 \u0431\u043e\u0433\u0430\u0442\u044b\u0439 \u0445\u043b\u043e\u0440\u043e\u0433\u0435\u043d\u043e\u0432\u043e\u0439 \u043a\u0438\u0441\u043b\u043e\u0442\u043e\u0439 \u044d\u043a\u0441\u0442\u0440\u0430\u043a\u0442 \u0437\u0435\u043b\u0451\u043d\u043e\u0433\u043e \u043a\u043e\u0444\u0435 \u043c\u0430\u0441\u0441\u0443 \u0442\u0435\u043b\u0430, \u0418\u041c\u0422 \u0438 \u043f\u0440\u043e\u0446\u0435\u043d\u0442 \u0436\u0438\u0440\u0430 \u0443 \u0432 \u043e\u0441\u0442\u0430\u043b\u044c\u043d\u043e\u043c \u0437\u0434\u043e\u0440\u043e\u0432\u044b\u0445 \u043b\u044e\u0434\u0435\u0439 \u0441 \u0438\u0437\u0431\u044b\u0442\u043e\u0447\u043d\u044b\u043c \u0432\u0435\u0441\u043e\u043c. \u041f\u0440\u0435\u0436\u043d\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u043b\u0438 \u043f\u043e\u0434\u0430\u0432\u043b\u0435\u043d\u0438\u0435 \u043f\u0438\u0449\u0435\u0432\u0430\u0440\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0430\u043c\u0438\u043b\u0430\u0437\u044b, \u0440\u0430\u0441\u0449\u0435\u043f\u043b\u044f\u044e\u0449\u0435\u0439 \u043a\u0440\u0430\u0445\u043c\u0430\u043b \u0434\u043e \u0441\u0430\u0445\u0430\u0440\u0430 \u0438 \u043f\u043e\u0432\u044b\u0448\u0430\u044e\u0449\u0435\u0439 \u0435\u0433\u043e \u0443\u0440\u043e\u0432\u0435\u043d\u044c. \u042d\u0442\u043e \u043c\u043e\u0436\u0435\u0442 \u0443\u043c\u0435\u043d\u044c\u0448\u0430\u0442\u044c \u0432\u0441\u0430\u0441\u044b\u0432\u0430\u043d\u0438\u0435 \u0441\u0430\u0445\u0430\u0440\u0430 \u0438 \u043e\u0431\u0449\u0435\u0435 \u043f\u043e\u0441\u0442\u0443\u043f\u043b\u0435\u043d\u0438\u0435 \u043a\u0430\u043b\u043e\u0440\u0438\u0439 (3).
\n\u0423\u0447\u0430\u0441\u0442\u0432\u043e\u0432\u0430\u043b\u0438 16 \u0447\u0435\u043b\u043e\u0432\u0435\u043a (8 \u043c\u0443\u0436\u0447\u0438\u043d, 8 \u0436\u0435\u043d\u0449\u0438\u043d) 22\u201346 \u043b\u0435\u0442 \u0441\u043e \u0441\u0440\u0435\u0434\u043d\u0438\u043c \u0438\u0441\u0445\u043e\u0434\u043d\u044b\u043c \u0418\u041c\u0422 28.22, \u0447\u0442\u043e \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0443\u0435\u0442 \u0438\u0437\u0431\u044b\u0442\u043e\u0447\u043d\u043e\u043c\u0443 \u0432\u0435\u0441\u0443, \u0438\u043b\u0438 \u043f\u0440\u0435\u0434\u043e\u0436\u0438\u0440\u0435\u043d\u0438\u044e.
\n\u042d\u043a\u0441\u0442\u0440\u0430\u043a\u0442 GCA\u00ae* \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043b 45.9% \u0445\u043b\u043e\u0440\u043e\u0433\u0435\u043d\u043e\u0432\u043e\u0439 \u043a\u0438\u0441\u043b\u043e\u0442\u044b.
\n\u0423\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u0438 \u043f\u043e\u043b\u0443\u0447\u0430\u043b\u0438 \u0432\u044b\u0441\u043e\u043a\u0443\u044e \u0434\u043e\u0437\u0443 350 \u043c\u0433 GCA\u00ae \u0442\u0440\u0438\u0436\u0434\u044b \u0432 \u0434\u0435\u043d\u044c (1 050 \u043c\u0433), \u043d\u0438\u0437\u043a\u0443\u044e \u2014 350 \u043c\u0433 \u0434\u0432\u0430\u0436\u0434\u044b (700 \u043c\u0433), \u043b\u0438\u0431\u043e 350 \u043c\u0433 \u043d\u0435\u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0433\u043e \u043f\u043b\u0430\u0446\u0435\u0431\u043e \u0442\u0440\u0438\u0436\u0434\u044b. \u041a\u0430\u0436\u0434\u044b\u0439 \u043a\u0443\u0440\u0441 \u043f\u0440\u043e\u0434\u043e\u043b\u0436\u0430\u043b\u0441\u044f 6 \u043d\u0435\u0434\u0435\u043b\u044c \u0441 \u043f\u043e\u0441\u043b\u0435\u0434\u0443\u044e\u0449\u0438\u043c\u0438 2 \u043d\u0435\u0434\u0435\u043b\u044f\u043c\u0438 \u0431\u0435\u0437 \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u043f\u0435\u0440\u0435\u0434 \u0441\u043b\u0435\u0434\u0443\u044e\u0449\u0438\u043c \u043f\u0435\u0440\u0438\u043e\u0434\u043e\u043c. \u0421\u0445\u0435\u043c\u0430 22 \u043d\u0435\u0434\u0435\u043b\u044c: \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u043d\u0435\u0434\u0435\u043b\u044f\u0445 0\u20136, \u0434\u0432\u0443\u0445\u043d\u0435\u0434\u0435\u043b\u044c\u043d\u044b\u0439 \u043f\u0435\u0440\u0435\u0440\u044b\u0432, \u043b\u0435\u0447\u0435\u043d\u0438\u0435 \u043d\u0430 \u043d\u0435\u0434\u0435\u043b\u044f\u0445 8\u201314, \u0435\u0449\u0451 \u0434\u0432\u0443\u0445\u043d\u0435\u0434\u0435\u043b\u044c\u043d\u044b\u0439 \u043f\u0435\u0440\u0435\u0440\u044b\u0432, \u0437\u0430\u0442\u0435\u043c \u043d\u0435\u0434\u0435\u043b\u0438 16\u201322.
\n\u041e\u0431\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u043f\u0440\u043e\u0432\u043e\u0434\u0438\u043b\u0438 \u043d\u0430 \u043d\u0435\u0434\u0435\u043b\u044f\u0445 0, 6, 8, 14, 16 \u0438 22. \u041a\u0430\u0436\u0434\u0430\u044f \u0433\u0440\u0443\u043f\u043f\u0430 \u043f\u043e\u043b\u0443\u0447\u0438\u043b\u0430 \u0432\u0441\u0435 \u0432\u0430\u0440\u0438\u0430\u043d\u0442\u044b \u043b\u0435\u0447\u0435\u043d\u0438\u044f.
\n\u0420\u0430\u0446\u0438\u043e\u043d \u043e\u0441\u0442\u0430\u0432\u0430\u043b\u0441\u044f \u043f\u043e\u0441\u0442\u043e\u044f\u043d\u043d\u044b\u043c, \u0431\u0435\u0437 \u0441\u0443\u0449\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0445 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u0439 \u043a\u0430\u043b\u043e\u0440\u0438\u0439\u043d\u043e\u0441\u0442\u0438. \u041f\u0440\u0438 \u043e\u0434\u0438\u043d\u0430\u043a\u043e\u0432\u043e\u043c \u043f\u043e\u0441\u0442\u0443\u043f\u043b\u0435\u043d\u0438\u0438 \u043a\u0430\u043b\u043e\u0440\u0438\u0439 \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0448\u0438\u0435 GCA\u00ae \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u043e \u0441\u043d\u0438\u0436\u0430\u043b\u0438 \u0432\u0435\u0441.
\n
\n\u041d\u0430\u0431\u043b\u044e\u0434\u0430\u0432\u0448\u0435\u0435\u0441\u044f \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435:
\n<\/u>
\n\u0412\u0435\u0441 \u0441\u043d\u0438\u0437\u0438\u043b\u0441\u044f \u043d\u0430 10.5%: \u0441 169.07 \u00b117.44 \u0434\u043e 151.35 \u00b117.2 \u0444\u0443\u043d\u0442\u0430.
\n\u0418\u041c\u0422 \u0441\u043d\u0438\u0437\u0438\u043b\u0441\u044f \u043d\u0430 10.3%: \u0441 28.22 \u00b10.91 \u0434\u043e 25.25 \u00b11.19 \u043a\u0433\/\u043c\u00b2.
\n\u041f\u0440\u043e\u0446\u0435\u043d\u0442 \u0436\u0438\u0440\u0430 \u0441\u043d\u0438\u0437\u0438\u043b\u0441\u044f \u043d\u0430 15.8%: \u0441 28.13 \u00b14.95% \u0434\u043e 23.69 \u00b14.95%.
\n\u0412\u0441\u0435 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044f \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u044b, p<0.0001, \u0447\u0442\u043e \u0438\u0441\u0442\u043e\u0447\u043d\u0438\u043a \u0442\u0440\u0430\u043a\u0442\u0443\u0435\u0442 \u043a\u0430\u043a \u0441\u0432\u0438\u0434\u0435\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u043e \u043f\u0440\u043e\u0442\u0438\u0432 \u0441\u043b\u0443\u0447\u0430\u0439\u043d\u043e\u0441\u0442\u0438 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432.
\n\u0421\u0440\u0435\u0434\u043d\u0438\u0439 \u0432\u0435\u0441 \u0438\u0437\u043c\u0435\u043d\u0438\u043b\u0441\u044f \u0441 72.86 \u0434\u043e 70.82 \u043a\u0433 \u043f\u0440\u0438 \u0432\u044b\u0441\u043e\u043a\u043e\u0439 \u0434\u043e\u0437\u0435, \u0441 71.25 \u0434\u043e 69.71 \u043a\u0433 \u043f\u0440\u0438 \u043d\u0438\u0437\u043a\u043e\u0439 \u0438 \u0441 72.15 \u0434\u043e 72.47 \u043a\u0433 \u043f\u0440\u0438 \u043f\u043b\u0430\u0446\u0435\u0431\u043e, \u0442\u043e \u0435\u0441\u0442\u044c \u043d\u0435\u043c\u043d\u043e\u0433\u043e \u0432\u044b\u0440\u043e\u0441. \u0418\u041c\u0422 \u0433\u0440\u0443\u043f\u043f GCA\u00ae \u043f\u0435\u0440\u0435\u0448\u0451\u043b \u0438\u0437 \u043f\u0440\u0435\u0434\u043e\u0436\u0438\u0440\u0435\u043d\u0438\u044f \u0432 \u043d\u043e\u0440\u043c\u0430\u043b\u044c\u043d\u044b\u0439 \u0434\u0438\u0430\u043f\u0430\u0437\u043e\u043d, \u0447\u0442\u043e \u0438\u0441\u0442\u043e\u0447\u043d\u0438\u043a \u0441\u0447\u0438\u0442\u0430\u0435\u0442 \u043f\u0435\u0440\u0441\u043f\u0435\u043a\u0442\u0438\u0432\u043d\u044b\u043c \u0434\u043b\u044f \u0437\u0434\u043e\u0440\u043e\u0432\u043e\u0433\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u044f \u0432\u0435\u0441\u0430. \u041d\u0438\u043a\u0442\u043e \u043d\u0435 \u0441\u043e\u043e\u0431\u0449\u0438\u043b \u043e \u043d\u0435\u0436\u0435\u043b\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u044d\u0444\u0444\u0435\u043a\u0442\u0430\u0445 GCA\u00ae (4).<\/p>\n

\n

\n

 <\/p>\n

*GCA\u00ae stands for Green Coffee Antioxidant and is the trademarked green coffee bean extract owned by Applied Food Sciences, Inc., and contains 45.9% chlorogenic acids
\nTatjana Djakovic, MS, graduated from\u00a0Roosevelt College in 2011, with concentration in biochemistry.\u00a0 Her research was in determining antioxidants and\u00a0macronutrients in herbal teas.\u00a0 She is originally from Gospic, Croatia and currently\u00a0resides in\u00a0Carol Stream, IL.<\/p>\n

References:<\/p>\n

1.\u00a0\u00a0\u00a0 World Health Organization (WHO). Fact Sheet 311. Geneva: WHO; 2011.<\/p>\n

2.\u00a0\u00a0\u00a0 Lopez-Garcia E, van Dam RM, Rajpathak S, Willett WC, Manson JE,vHu FB. Changes in caffeine intake and long-term weight change in men and women. Am J Clin Nutr. 2006;83:674\u2013680.<\/p>\n

3.\u00a0\u00a0\u00a0 Narita Y, Inouye KJ. Kinetic analysis and mechanism on the inhibition of chlorogenic acid and its components against porcine pancreas alpha-amylase isozymes I and II. J Agric Food Chem. 2009;57: 9218\u20139225.<\/p>\n

4.\u00a0\u00a0\u00a0 Vinson, Joe A., Bryan R. Burnham, and Mysore V. Nagendran. “Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects.”Diabetes, metabolic syndrome and obesity: targets and therapy\u00a05 (2012): 21.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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