{"id":16764,"date":"2024-06-23T11:10:23","date_gmt":"2024-06-23T08:10:23","guid":{"rendered":"https:\/\/marshal.co.il\/?p=16764"},"modified":"2026-10-29T00:52:56","modified_gmt":"2026-10-28T21:52:56","slug":"b-vitamins-and-blood-pressure","status":"publish","type":"post","link":"https:\/\/marshal.co.il\/en\/b-vitamins-and-blood-pressure\/","title":{"rendered":"B vitamins and blood pressure"},"content":{"rendered":"<div>By Marcia J. Egles, MD, August 6, 2013 from A Nutrient-Wide Association Study on Blood Pressure by Ioanna Tzoulaki\u00a0et al in Circulation. 2012;126:2456-2464 (1)<\/div>\n<p>&nbsp;<\/p>\n<p dir=\"ltr\">\n<p>Taking B vitamins may have a favourable effect on blood pressure, according to a statistical study (1) published by the American Heart Association.<br \/>\nHypertension, also called high blood pressure, is a leading cause of heart disease worldwide (2). Heart disease and stroke risk rises across blood-pressure levels; even high-normal pressure carries appreciable risk (1). Dietary habits involving salt are known to raise blood pressure (3), but despite research, the effects of many other nutrients remain unclear (1).<br \/>\nA broad nutrient-based study offers a more comprehensive statistical approach to investigating hypertension than studying one nutrient at a time.<br \/>\nTwo large studies, INTERMAP (4) and NHANES (National Health and Nutrition Examination Survey) (5), provided databases for this broad nutrient investigation. INTERMAP was a collaborative study of macronutrients and micronutrients, reported in 2003. It used cross-sectional data on 4,680 men and women aged 40\u201359 from 17 countries, including China, Japan and the United States, as described in the source. Participant interviews recorded food and supplement intake, from which 82 different nutrients were derived.<br \/>\nTo validate these findings, NHANES conducted extensive ongoing observations in the United States in 1999\u20132006 in a population similar to INTERMAP\u2019s. The aim was to confirm earlier findings and identify previously unreported associations between nutrients and hypertension. Alcohol intake was again associated with higher pressure. The link between greater sodium intake relative to potassium and higher pressure was also reinforced (4,5).<br \/>\nPeople consuming phosphorus, magnesium and non-haem iron were more likely to have lower blood pressure. New findings not identified in earlier studies concerned B vitamins: thiamine (B1), folic acid (B9) and riboflavin (B2) were inversely associated with higher blood pressure, like the minerals above.<br \/>\nIdentifying an association between a nutrient and blood pressure does not establish causation, but can guide future studies.<br \/>\nFurther clinical evaluation is needed to determine whether B vitamins can help prevent cardiovascular disease caused by high blood pressure (1).<\/p>\n<div>\n<p>&nbsp;<\/p>\n<p dir=\"ltr\">Reference:<\/p>\n<p dir=\"ltr\">1.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Tzoulaki, Ioanna , et al. A Nutrient-Wide Association Study on Blood Pressure, Circulation. 2012;126:2456-2464; originally published online October 23, 2012; doi: 10.1161\/CIRCULATIONAHA.112.114058 \u00a0Circulation is published by the American Heart Association.<\/p>\n<p dir=\"ltr\">2.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Hajjar I, Kotchen JM, Kotchen TA. Hypertension: trends in prevalence, incidence, and control. Annu Rev Public Health. 2006;27:465-9<\/p>\n<p dir=\"ltr\">3.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Sacks, Frank MD et al. Effects on Blood Pressure of Reduced Dietary Sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet. N Engl J Med 2001; 344:3-10. DOI: 10.1056\/NEJM200101043440101<\/p>\n<p dir=\"ltr\">4.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Stamler J, Elliott P, Dennis B, Dyer AR, Kesteloot H, Liu K, Ueshima H, Zhou BF; INTERMAP Research Group. INTERMAP: background, aims, design, methods, and descriptive statistics (nondietary). J Hum Hypertens. 2003;17:591\u2013 608.<\/p>\n<p dir=\"ltr\">5.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Centers for Disease Control and Prevention (CDC). National Health and Nutrition Examination Survey. http:\/\/www cdc gov\/nchs\/nhanes\/ 2011; Accessed 03\/06\/2012.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>By Marcia J. Egles, MD, August 6, 2013 from A Nutrient-Wide Association Study on Blood Pressure by Ioanna Tzoulaki\u00a0et al<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[727,733],"tags":[],"class_list":["post-16764","post","type-post","status-publish","format-standard","hentry","category-727","category-733"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>B vitamins and blood pressure - Marshal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/marshal.co.il\/en\/b-vitamins-and-blood-pressure\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"B vitamins and blood pressure - Marshal\" \/>\n<meta property=\"og:description\" content=\"By Marcia J. 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