{"id":16752,"date":"2024-06-23T11:09:09","date_gmt":"2024-06-23T08:09:09","guid":{"rendered":"https:\/\/marshal.co.il\/?p=16752"},"modified":"2026-10-29T00:51:31","modified_gmt":"2026-10-28T21:51:31","slug":"new-findings-on-turmeric-and-cardiovascular-health","status":"publish","type":"post","link":"https:\/\/marshal.co.il\/en\/new-findings-on-turmeric-and-cardiovascular-health\/","title":{"rendered":"New findings on turmeric and cardiovascular health"},"content":{"rendered":"<div>By Jessica Patella, ND abstracted on June 27, 2013 from \u201cCurcumin ameliorates arterial dysfunction and oxidative stress with aging\u201d from the 48th volume in 2013 of Experimental Gerontology<\/div>\n<p>Cardiovascular disease is the leading cause of death in the United States (1,2). Ageing is one of its main risk factors (1,2). A recent mouse study found that curcumin supplementation improved cardiovascular signs associated with ageing (1).<br \/>\nTurmeric is commonly used in Indian cooking and traditional Ayurvedic medicine (3). The source describes it as safe for human use as a spice, with antioxidant effects (1,3). Oxidative processes are considered major contributors to ageing. This study examined turmeric\u2019s antioxidant effects on ageing in mice and their relationship to the cardiovascular system (1).<br \/>\nThe study included young mice (4\u20136 months), compared with a 25-year-old human, and older mice (26\u201328 months), compared with a 75-year-old human (1).<br \/>\nThe mice were divided into four groups: young controls (n=5), young curcumin-treated mice (n=7), older controls (n=10), and older curcumin-treated mice (n=10).<br \/>\nThe curcumin groups received daily dietary curcumin at a dose described as equivalent to 14\u201319 grams for a 60-kg human; controls received the same diet without curcumin. The study lasted 4 weeks (1).<br \/>\nAt baseline, as expected, the older mice showed more cardiovascular signs of ageing. Arterial stiffness, measured by aortic pulse wave velocity, was higher in older mice (448 \u00b115 versus 349 \u00b115 cm\/s). After 4 weeks, older mice receiving dietary curcumin showed results similar to young mice (386 \u00b115 cm\/s; p&lt;0.05), suggesting improved arterial elasticity, an important factor in cardiovascular health (1).<br \/>\nAnother sign of ageing is endothelial dysfunction. The endothelium lines the inside of blood vessels and arteries. When it does not function properly, arteries do not dilate normally, potentially causing high blood pressure (1). After 4 weeks of curcumin-supplemented diet, endothelial function in older mice returned to levels found in young mice: endothelium-dependent acetylcholine-induced arterial dilation was 92 \u00b12%, p&lt;0.05.<br \/>\nThe young curcumin-supplemented mice showed no changes between baseline and week 4, suggesting that curcumin affected only older mice, apparently by reducing oxidative processes (1).<br \/>\nIn conclusion, curcumin supplementation appeared to improve important age-related cardiovascular signs in mice, including arterial stiffness and endothelial function. The source describes this as the first study showing that curcumin supplementation could reduce or improve age-related arterial stiffness and endothelial dysfunction (1), suggesting a possible approach to reducing cardiovascular risk (1).<br \/>\nFurther research is needed to establish whether these findings also apply to humans.<\/p>\n<p dir=\"ltr\">\n<div>\n<p>&nbsp;<\/p>\n<p dir=\"ltr\">REFERENCES:<\/p>\n<p dir=\"ltr\">1.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Fleenor B, et al.\u00a0Curcumin ameliorates arterial dysfunction and oxidative stress with aging. 2013 Experimental Gerontology 48: 269-276.<\/p>\n<p dir=\"ltr\">2.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Roger, V.L., et al. Heart disease and stroke statistics 2012 update: a report from the American Heart Association. 2012 Circulation 125, e2\u2013e220.<\/p>\n<p dir=\"ltr\">3.\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Miriyala, S., et al. Cardioprotective effects of curcumin. 2007 Adv. Exp. Med. Biol. 595, 359\u2013377<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>By Jessica Patella, ND abstracted on June 27, 2013 from \u201cCurcumin ameliorates arterial dysfunction and oxidative stress with aging\u201d from<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[727,733],"tags":[],"class_list":["post-16752","post","type-post","status-publish","format-standard","hentry","category-727","category-733"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New findings on turmeric and cardiovascular health - Marshal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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