{"id":16623,"date":"2024-06-23T11:18:22","date_gmt":"2024-06-23T08:18:22","guid":{"rendered":"https:\/\/marshal.co.il\/?p=16623"},"modified":"2026-10-29T00:05:49","modified_gmt":"2026-10-28T21:05:49","slug":"vitamin-e-improves-nerve-health-in-patients-with-diabetes","status":"publish","type":"post","link":"https:\/\/marshal.co.il\/en\/vitamin-e-improves-nerve-health-in-patients-with-diabetes\/","title":{"rendered":"Vitamin E improves nerve health in patients with diabetes"},"content":{"rendered":"
By Greg Arnold, DC, CSCS, August 27, 2014, abstracted from \u201cAssessment of antioxidant supplementation on the neuropathic pain score and quality of life in diabetic neuropathy patients – a randomized controlled study\u201d in the February 2014 issue of Pharmacology Reports.<\/div>\n

Diabetes may cause diabetic neuropathy, which manifests as nerve damage in the hands and feet. Half of all people with diabetes develop diabetic neuropathy (1). It can substantially reduce their quality of life, making ways to treat nerve damage a high priority.<\/p>\n

A new study (2) suggests that vitamin E may benefit nervous-system health in patients with diabetes. Ninety-two patients diagnosed with diabetic neuropathy received either standard medical treatment for diabetes with neuropathy (blood-sugar-stabilizing medication, 46 patients) or standard treatment plus 400 IU vitamin E daily (46 patients), for 12 weeks.<\/p>\n

Along with random blood samples measuring blood sugar, each participant completed questionnaires on physical health (3) and nerve pain. The nerve-pain questionnaires were combined with physical-examination data to produce a cumulative neuropathic pain score (4).<\/p>\n

After 12 weeks, statistically significant improvement was noted only in the vitamin E group:<\/p>\n\n\n\n\n\n
Treatment group<\/strong><\/td>\nPhysical health score before vitamin E<\/strong><\/td>\nPhysical health score after vitamin E<\/strong><\/td>\nChange<\/strong><\/td>\np-value<\/strong><\/td>\n<\/tr>\n
\n

Vitamin\u00a0E<\/span><\/p>\n<\/td>\n

\n

59.1<\/span><\/p>\n<\/td>\n

\n

64.6<\/span><\/p>\n<\/td>\n

\n

+ 9.3 %<\/span><\/p>\n<\/td>\n

\n

p<\/span><\/em>\u00a0< 0.05<\/span><\/p>\n<\/td>\n<\/tr>\n

Placebo<\/td>\n\n

53.3<\/span><\/p>\n<\/td>\n

\n

55.8<\/span><\/p>\n<\/td>\n

\n

+4.7%<\/span><\/p>\n<\/td>\n

\n

p<\/span><\/em>\u00a0> 0.05<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n
Treatment group<\/strong><\/td>\n\n

Random blood glucose before vitamin\u00a0E<\/span>\u00a0(mg\/dL<\/span>)\u00a0<\/strong><\/p>\n<\/td>\n

\n

Random blood glucose after vitamin\u00a0E<\/span>\u00a0(mg\/dL<\/span>)<\/strong><\/p>\n<\/td>\n

Change<\/strong><\/td>\n\n

p-<\/span><\/em>value<\/span><\/strong><\/p>\n<\/td>\n<\/tr>\n

Vitamin E<\/td>\n161<\/td>\n139<\/td>\n\n

-13.7%<\/span><\/p>\n<\/td>\n

\n

p<\/span><\/em>\u00a0< 0.05<\/span><\/p>\n<\/td>\n<\/tr>\n

Placebo<\/td>\n149<\/td>\n142<\/td>\n\n

-4.7%<\/span><\/p>\n<\/td>\n

\n

p<\/span><\/em>\u00a0> 0.05<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Neuropathic pain measures showed significant improvement only in patients over age 50:<\/p>\n\n\n\n\n\n
Treatment group<\/td>\n\n

Neuropathic pain score before vitamin\u00a0<\/strong>E<\/span><\/strong>\u00a0(age >50)<\/strong><\/p>\n<\/td>\n

\n

Neuropathic pain score after vitamin\u00a0<\/strong>E<\/span><\/strong>\u00a0(age >50)<\/strong><\/p>\n<\/td>\n

Change<\/td>\n\n

p-<\/span><\/em><\/strong>value<\/span><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

Vitamin\u00a0E<\/span><\/p>\n<\/td>\n

\n

24.5<\/p>\n<\/td>\n

\n

16.0<\/p>\n<\/td>\n

\n

-34.7%<\/span><\/p>\n<\/td>\n

\n

p<\/span><\/em>\u00a0< 0.05<\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Placebo<\/p>\n<\/td>\n

\n

26.54<\/p>\n<\/td>\n

\n

24.5<\/p>\n<\/td>\n

\n

-17%<\/span><\/p>\n<\/td>\n

\n

p<\/span><\/em>\u00a0> 0.05<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

The researchers concluded that \u201cVitamin\u00a0E<\/span>\u00a0is a natural antioxidant and was found effective in reducing pain in patients with diabetic neuropathy.\u201d<\/p>\n

\n

\n

 <\/p>\n

Reference:<\/p>\n

1.\u00a0\u00a0\u00a0\u00a0\u00a0\u201cNerve damage (Neuropathy)\u201d posted on the American Diabetes Association website<\/p>\n

2.\u00a0\u00a0\u00a0\u00a0\u00a0Rajanandh MG.\u00a0Assessment\u00a0of antioxidant supplementation on the neuropathic pain score and quality of life in diabetic neuropathy patients – a randomized controlled study.\u00a0Pharmacol Rep\u00a02014 Feb;66(1):44-8. doi: 10.1016\/j.pharep.2013.08.003. Epub 2014 Jan 30<\/p>\n

3.\u00a0\u00a0\u00a0\u00a0\u00a0\u201c36-Item Short Form Survey from the RAND Medical Outcomes Study\u201d posted on the RAND website<\/p>\n

4.\u00a0\u00a0\u00a0\u00a0\u00a0Rog DJ.\u00a0Validation and reliability of the Neuropathic Pain Scale (NPS) in multiple sclerosis.\u00a0Clin J Pain. 2007 Jul-Aug;23(6):473-81<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

By Greg Arnold, DC, CSCS, August 27, 2014, abstracted from \u201cAssessment of antioxidant supplementation on the neuropathic pain score and<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[727,736],"tags":[],"class_list":["post-16623","post","type-post","status-publish","format-standard","hentry","category-727","category-736"],"acf":[],"yoast_head":"\nVitamin E improves nerve health in patients with diabetes - Marshal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/marshal.co.il\/en\/vitamin-e-improves-nerve-health-in-patients-with-diabetes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vitamin E improves 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