{"id":16485,"date":"2024-06-23T10:18:42","date_gmt":"2024-06-23T07:18:42","guid":{"rendered":"https:\/\/marshal.co.il\/?p=16485"},"modified":"2026-10-28T23:31:15","modified_gmt":"2026-10-28T20:31:15","slug":"rhodiola-rosea-for-mild-to-moderate-depression-a-clinical-trial","status":"publish","type":"post","link":"https:\/\/marshal.co.il\/en\/rhodiola-rosea-for-mild-to-moderate-depression-a-clinical-trial\/","title":{"rendered":"Rhodiola rosea for mild to moderate depression: a clinical trial"},"content":{"rendered":"<p dir=\"ltr\"><em>Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Article in Nordic Journal of Psychiatry \u00b7 February 2007<\/em><\/p>\n<p>A randomized, double-blind, placebo-controlled study conducted in Oslo, Sweden, and published in Nord J Psychiatry in 2007 examined the efficacy, safety and effects of rhodiola extract in mild to moderate depression.<\/p>\n<p>The study included 89 men and women aged 18\u201370 with episodes of mild to moderate depression according to HAMD (Hamilton Rating Scale for Depression), and lasted 42 days.<\/p>\n<p>Participants were divided into three groups:<\/p>\n<ul>\n<li>Group A (31 participants) took 340 mg rhodiola extract daily.<\/li>\n<li>Group B (29 participants) took 340 mg rhodiola extract twice daily (680 mg total).<\/li>\n<li>Group C (29 participants) took placebo twice daily.<\/li>\n<\/ul>\n<h2>Study results:<\/h2>\n<p>Groups A and B improved in overall depression, insomnia, emotional stability and physical sensations compared with placebo (group C).<\/p>\n<p>At baseline (day 0), the mean HAMD depression score in the three groups was 24.5.<\/p>\n<p>At the end (day 42), the score fell to 15.97 in group A and 16.72 in group B. Group C showed no statistically significant change (23.41).<\/p>\n<p>No adverse effects from rhodiola extract or placebo were observed in any group.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.nutri-care.co.il\/userfiles\/image\/Rhodiola.jpg\" alt=\"\" \/><\/p>\n<h2>Conclusions:<\/h2>\n<p>Rhodiola rosea extract has a beneficial effect on mild to moderate symptoms of depression without adverse effects.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Article in Nordic Journal<\/p>\n","protected":false},"author":3,"featured_media":7323,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[727,728],"tags":[],"class_list":["post-16485","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-727","category-728"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rhodiola rosea for mild to moderate depression: a clinical trial - Marshal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/marshal.co.il\/en\/rhodiola-rosea-for-mild-to-moderate-depression-a-clinical-trial\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rhodiola rosea for mild to moderate depression: a clinical trial - Marshal\" \/>\n<meta property=\"og:description\" content=\"Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. 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