{"id":16685,"date":"2024-06-23T11:09:47","date_gmt":"2024-06-23T08:09:47","guid":{"rendered":"https:\/\/marshal.co.il\/?p=16685"},"modified":"2026-10-29T00:24:02","modified_gmt":"2026-10-28T21:24:02","slug":"%d8%a7%d9%86%d8%ae%d9%81%d8%a7%d8%b6-%d9%81%d9%8a%d8%aa%d8%a7%d9%85%d9%8a%d9%86-d-%d9%8a%d8%b2%d9%8a%d8%af-%d8%ae%d8%b7%d8%b1-%d8%a7%d9%84%d9%88%d9%81%d8%a7%d8%a9-%d9%84%d8%af%d9%89-%d9%85%d8%b1%d8%b6","status":"publish","type":"post","link":"https:\/\/marshal.co.il\/ar\/%d8%a7%d9%86%d8%ae%d9%81%d8%a7%d8%b6-%d9%81%d9%8a%d8%aa%d8%a7%d9%85%d9%8a%d9%86-d-%d9%8a%d8%b2%d9%8a%d8%af-%d8%ae%d8%b7%d8%b1-%d8%a7%d9%84%d9%88%d9%81%d8%a7%d8%a9-%d9%84%d8%af%d9%89-%d9%85%d8%b1%d8%b6\/","title":{"rendered":"\u0627\u0646\u062e\u0641\u0627\u0636 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u064a\u0632\u064a\u062f \u062e\u0637\u0631 \u0627\u0644\u0648\u0641\u0627\u0629 \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 \u0627\u0644\u0639\u062f\u0648\u0649 \u0627\u0644\u0634\u062f\u064a\u062f\u0629"},"content":{"rendered":"<div>By Greg Arnold, DC, CSCS, September 18, 2014, abstracted from \u201cDeficiency in 25-hydroxyvitamin d and 30-day mortality in patients with severe sepsis and septic shock.\u201d<\/div>\n<p>\u064a\u0646\u062a\u062c \u0627\u0644\u0625\u0646\u062a\u0627\u0646 \u0639\u0646 \u062f\u062e\u0648\u0644 \u0627\u0644\u0628\u0643\u062a\u064a\u0631\u064a\u0627 \u0625\u0644\u0649 \u0645\u062c\u0631\u0649 \u0627\u0644\u062f\u0645 \u0648\u062a\u0643\u0627\u062b\u0631\u0647\u0627. \u0648\u064a\u0638\u0647\u0631 \u0643\u0639\u062f\u0648\u0649 \u0634\u062f\u064a\u062f\u0629 \u0642\u062f \u062a\u0635\u0628\u062d \u0645\u0647\u062f\u062f\u0629 \u0644\u0644\u062d\u064a\u0627\u0629 \u0628\u0633\u0631\u0639\u0629\u060c \u0645\u0639 \u062d\u0645\u0649 \u0648\u0642\u0634\u0639\u0631\u064a\u0631\u0629. \u0648\u0641\u064a \u0627\u0644\u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0634\u062f\u064a\u062f\u0629\u060c \u0642\u062f \u064a\u0646\u062e\u0641\u0636 \u0627\u0644\u0636\u063a\u0637 \u0648\u062a\u0636\u0639\u0641 \u0639\u0636\u0644\u0629 \u0627\u0644\u0642\u0644\u0628\u060c \u0641\u062a\u062d\u062f\u062b \u0635\u062f\u0645\u0629 \u0625\u0646\u062a\u0627\u0646\u064a\u0629 \u0648\u0641\u0634\u0644 \u0623\u0639\u0636\u0627\u0621. \u0648\u0639\u0646\u062f \u062d\u062f\u0648\u062b \u0627\u0644\u0635\u062f\u0645\u0629\u060c \u064a\u0632\u062f\u0627\u062f \u062e\u0637\u0631 \u0627\u0644\u0648\u0641\u0627\u0629 \u0643\u062b\u064a\u0631\u064b\u0627 (1).<\/p>\n<p>\u0644\u0644\u0623\u0633\u0641\u060c \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0641\u0639\u0651\u0627\u0644\u0629 \u0644\u062e\u0641\u0636 \u0627\u0644\u0648\u0641\u0627\u0629 \u0641\u064a \u0627\u0644\u0625\u0646\u062a\u0627\u0646 \u0642\u0644\u064a\u0644\u0629 (2). \u0648\u062a\u0634\u064a\u0631 \u062f\u0631\u0627\u0633\u0629 \u062c\u062f\u064a\u062f\u0629 (3) \u0625\u0644\u0649 \u0623\u0646 \u0643\u0641\u0627\u064a\u0629 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u0641\u064a \u0627\u0644\u062f\u0645 \u0642\u062f \u062a\u0633\u0627\u0639\u062f. \u062d\u064f\u0644\u0651\u0644\u062a \u0633\u062c\u0644\u0627\u062a 121 \u0645\u0631\u064a\u0636\u064b\u0627 \u0623\u064f\u062f\u062e\u0644\u0648\u0627 \u0627\u0644\u0645\u0633\u062a\u0634\u0641\u0649 \u0628\u0625\u0646\u062a\u0627\u0646 \u0634\u062f\u064a\u062f \u0623\u0648 \u0635\u062f\u0645\u0629 \u0625\u0646\u062a\u0627\u0646\u064a\u0629\u060c \u0648\u0642\u0650\u064a\u0633 \u0627\u0644\u0628\u0642\u0627\u0621 \u062e\u0644\u0627\u0644 \u0623\u0648\u0644 30 \u064a\u0648\u0645\u064b\u0627. \u0648\u0639\u064f\u0631\u0651\u0641 \u0627\u0644\u0646\u0642\u0635 \u0628\u0645\u0633\u062a\u0648\u0649 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u064a\u0633\u0627\u0648\u064a \u0623\u0648 \u064a\u0642\u0644 \u0639\u0646 15 \u0646\u0627\u0646\u0648\u063a\u0631\u0627\u0645\/\u0645\u0644.<\/p>\n<p>\u0643\u0627\u0646 \u0644\u062f\u0649 \u0627\u0644\u064054% \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u0646\u0642\u0635 (65 \u0645\u0646 121) \u062e\u0637\u0631 \u0648\u0641\u0627\u0629 \u0623\u0639\u0644\u0649 \u0628\u0646\u0633\u0628\u0629 170% \u062e\u0644\u0627\u0644 30 \u064a\u0648\u0645\u064b\u0627 \u0645\u0646 \u0627\u0644\u062f\u062e\u0648\u0644 (p=0.02). \u0648\u062a\u0648\u0641\u064a 37% \u0645\u0646 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0627\u0644\u0646\u0642\u0635 \u062e\u0644\u0627\u0644 30 \u064a\u0648\u0645\u064b\u0627\u060c \u0645\u0642\u0627\u0628\u0644 20% \u0645\u0646 \u0623\u0635\u062d\u0627\u0628 \u0627\u0644\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629. \u0648\u0628\u0639\u062f 90 \u064a\u0648\u0645\u064b\u0627\u060c \u062a\u0648\u0641\u064a 51% \u0645\u0646 \u0630\u0648\u064a \u0627\u0644\u0646\u0642\u0635 \u0645\u0642\u0627\u0628\u0644 25% \u0645\u0646 \u0630\u0648\u064a \u0627\u0644\u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0637\u0628\u064a\u0639\u064a.<\/p>\n<p>\u0641\u064a \u0645\u0646\u0627\u0642\u0634\u0629 \u0627\u0644\u0622\u0644\u064a\u0629\u060c \u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0644\u0641\u064a\u062a\u0627\u0645\u064a\u0646 D. \u0641\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u0627\u0639\u0629 \u062a\u0632\u064a\u062f \u062d\u0633\u0627\u0633\u064a\u062a\u0647\u0627 \u0644\u0647 (4\u060c5)\u060c \u0648\u0647\u0648 \u064a\u0632\u064a\u062f \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062a\u0627\u0626\u064a\u0629 \u0648\u064a\u0642\u0644\u0651\u0644 \u0628\u0631\u0648\u062a\u064a\u0646\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u0633\u0645\u0627\u0629 \u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a (6).<\/p>\n<p>\u0623\u0642\u0631\u0651 \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0628\u0642\u064a\u0648\u062f: \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u062a\u062d\u0644\u064a\u0644 \u0627\u0633\u062a\u0639\u0627\u062f\u064a \u0644\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0648\u0644\u064a\u0633\u062a \u062a\u062c\u0631\u0628\u0629 \u0645\u0633\u062a\u0642\u0628\u0644\u064a\u0629 \u0641\u0639\u0644\u064a\u0629 (7)\u060c \u0628\u0639\u064a\u0646\u0629 \u0635\u063a\u064a\u0631\u0629 \u0645\u0646 121 \u0645\u0631\u064a\u0636\u064b\u0627\u060c \u0648\u0637\u0631\u064a\u0642\u0629 \u0645\u062b\u064a\u0631\u0629 \u0644\u0644\u062a\u0633\u0627\u0624\u0644 \u0644\u0642\u064a\u0627\u0633 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D. \u0648\u0645\u0639 \u0630\u0644\u0643\u060c \u062e\u0644\u0635\u0648\u0627 \u0625\u0644\u0649 \u0623\u0646 \u0645\u0631\u0636\u0649 \u0627\u0644\u0625\u0646\u062a\u0627\u0646 \u0627\u0644\u0634\u062f\u064a\u062f \u0623\u0648 \u0627\u0644\u0635\u062f\u0645\u0629 \u0627\u0644\u0625\u0646\u062a\u0627\u0646\u064a\u0629 \u0642\u062f \u064a\u0648\u0627\u062c\u0647\u0648\u0646 \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0648\u0641\u0627\u0629 \u0644\u0623\u064a \u0633\u0628\u0628 \u062e\u0644\u0627\u0644 30 \u064a\u0648\u0645\u064b\u0627 \u0628\u0627\u0644\u0645\u0633\u062a\u0634\u0641\u0649\u060c \u0645\u0639 \u0627\u062d\u062a\u0645\u0627\u0644 \u062e\u0641\u0636 \u0627\u0644\u062e\u0637\u0631 \u0628\u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0643\u0627\u0641\u064a\u0629 \u0645\u0646 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D.<\/p>\n<p dir=\"ltr\">\n<div>\n<p>&nbsp;<\/p>\n<p dir=\"ltr\">Reference:<\/p>\n<p dir=\"ltr\">1.\u00a0\u00a0\u00a0\u00a0\u00a0\u201cSepsis Questions and Answers\u201d posted on the CDC website<\/p>\n<p dir=\"ltr\">2.\u00a0\u00a0\u00a0\u00a0\u00a0Rivers E, Nguyen B, Havstad S, et al; Early Goal-Directed Therapy Collaborative Group. Early goal-directed therapy in the treatment of severe sepsis and septic shock.\u00a0N Engl J Med.\u00a02001;345(19):1368-1377.<\/p>\n<p dir=\"ltr\">3.\u00a0\u00a0\u00a0\u00a0\u00a0Rech MA.\u00a0Deficiency in 25-hydroxyvitamin d and 30-day mortality in patients with severe sepsis and septic shock.\u00a0Am J Crit Care\u00a02014 Sep;23(5):e72-9. doi: 10.4037\/ajcc2014723<\/p>\n<p dir=\"ltr\">4.\u00a0\u00a0\u00a0\u00a0\u00a0Holick MF. Vitamin D deficiency.\u00a0N Engl J Med.\u00a02007;357(3): 266-281.<\/p>\n<p dir=\"ltr\">5.\u00a0\u00a0\u00a0\u00a0\u00a0White JH. Vitamin D metabolism and signaling in the immune system.\u00a0Rev Endocr Metab Disord.\u00a02012;13(1):21-29<\/p>\n<p dir=\"ltr\">6.\u00a0\u00a0\u00a0\u00a0\u00a0Joseph RW, Bayraktar UD, Kim TK, et al. Vitamin D receptor upregulation in alloreactive human T cells.\u00a0Hum Immunol. 2012;73(7):693-698.<\/p>\n<p dir=\"ltr\">7.\u00a0\u00a0\u00a0\u00a0\u00a0Heijboer AC, Blankenstein MA, Kema IP, Buijs MM. Accuracy of 6 routine 25-hydroxyvitamin D assays: influence of vitamin D binding protein concentration.\u00a0Clin Chem.\u00a02012;58(3): 543-548<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>By Greg Arnold, DC, CSCS, September 18, 2014, abstracted from \u201cDeficiency in 25-hydroxyvitamin d and 30-day mortality in patients with<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[729,734],"tags":[],"class_list":["post-16685","post","type-post","status-publish","format-standard","hentry","category-729","category-734"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u0627\u0646\u062e\u0641\u0627\u0636 \u0641\u064a\u062a\u0627\u0645\u064a\u0646 D \u064a\u0632\u064a\u062f \u062e\u0637\u0631 \u0627\u0644\u0648\u0641\u0627\u0629 \u0644\u062f\u0649 \u0645\u0631\u0636\u0649 \u0627\u0644\u0639\u062f\u0648\u0649 \u0627\u0644\u0634\u062f\u064a\u062f\u0629 - 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